He begins the first full defence of his unified UFC Middleweight Championship belt, and will be confident of doing so against Romero.
The Cuban star has fought just four times since 2016 and lost three of those bouts, with his sole victory over Luke Rockhold failing to secure the Middleweight title due to being missing weight ahead of the event.
Romero will be desperate for a return to the top, but faces a major challenge in the shape of Adesanya.
RadioTimes.com has rounded up everything you need to know about how to watch UFC 248 on TV and online.
What time does UFC 248 start?
TV coverage of the UFC 248 main card will start at 3:00am (UK time) in the early hours of Sunday 8th March 2020.
The preliminary card will be broadcast from 1:00am (UK time).
Where is UFC 248 held?
The event will be held at the T-Mobile Arena in Las Vegas, Nevada, USA.
UFC 248 card
Main Card
Middleweight: Israel Adesanya (c) v Yoel Romero
Women's: Strawweight Zhang Weili (c) v Joanna Jędrzejczyk
Lightweight: Beneil Dariush v Drakkar Klose
Welterweight: Neil Magny v Li Jingliang
Welterweight: Alex Oliveira v Max Griffin
Preliminary Card
Bantamweight: Sean O'Malley v José Alberto Quiñónez
Lightweight: Mark Madsen v Austin Hubbard
Middleweight: Rodolfo Vieira v Saparbek Safarov
Middleweight: Gerald Meerschaert v Deron Winn
Early Preliminary Card
Women's Strawweight: Emily Whitmire v Polyana Viana
Featherweight: Giga Chikadze v Jamall Emmers
Bantamweight: Danaa Batgerel v Guido Cannetti
What channel is UFC 248 on?
The event will be shown live on BT Sport 2 from 1:00am.
There are multiple ways to get BT Sport. If you already have BT Broadband, you can add BT TV and Sport to your existing contract for just £15.00 per month. New customers or Sky, TalkTalk and Virgin subscribers can also access BT Sport with a host of great deals.
How to live stream UFC 248
You can watch the event with a BT Sport monthly pass without signing up to a contract.
Regular subscribers can also stream matches via the BT Sport website or BT Sport app on a variety of devices including laptops, smartphones and tablets.
How to watch UFC 248 in US
US fans can watch the event live in the US via ESPN+.
On its own, EPSN+ costs $4.99 per month or $49.99 per year. You can purchase UFC 247 only for $64.99 or combine it with a ESPN+ annual subscription for $84.98, an over 25% saving.
